Which Amendment protects against unreasonable search and seizure?

The Fourth Amendment is the correct answer because it specifically addresses the protection against unreasonable searches and seizures. It establishes the principle that law enforcement must have probable cause and, in most cases, a warrant issued by a judge to search an individual's property or seize their belongings. This amendment is a crucial aspect of individual privacy rights in the United States, ensuring that citizens are not subjected to arbitrary or invasive actions by the government.

The other amendments listed do not pertain to search and seizure. The Fifth Amendment deals with rights related to criminal proceedings, including protection against self-incrimination and double jeopardy. The Sixth Amendment focuses on the rights of criminal defendants, such as the right to a fair trial and legal representation. The Second Amendment pertains to the right to keep and bear arms. Each of these amendments addresses different aspects of individual rights and legal protections.